Mood disorders are characterized as a psychological disorder involving an elevation or depression of an individual’s mood. Mood disorders include depression, a mild form of bipolar disorder, seasonal affective disorder (SAD) and hyperactivity.
Psychotic disorders are considered severe mental disorders which result in abnormal thinking and perceptions. Schizophrenia is a psychotic disorder that causes delusions and hallucinations.
Several studies have found a relationship between vitamin D deficiency and both mood and psychotic disorders. However, results regarding vitamin D deficiency and specific psychiatric diagnosis have been conflicting.
A recent cohort study conducted in Marseille, France aimed to determine if vitamin D deficiency severity is related to specific psychiatric diagnoses.
Researchers admitted 82 inpatients from the Assistance Publique – Hôpitaux deMarseille with mood disorders and schizophrenia in the study. They retrospectively reviewed medical charts containing all clinical and biological assessments from the patients.
The researchers found that 37.8% of individuals were severely vitamin D deficient, which was defined as less than 5 ng/ml. Vitamin D deficiency was also significantly more severe in patients with mood disorders when compared to those who were schizophrenia (p = 0.004). This relationship remained significant after adjusting for common confounding variables (p = 0.007).
The researchers concluded,
“Patients with mood disorders (major depression, bipolar disorders and dysthymia) have more severe hypovitaminosis D than patients with schizophrenia, independently of season of measurement, phototype, body mass index and physical activity.”
Belzeaux, Raoul et. Al. Mood disorders are associated with a more severe hypovitaminosis D than schizophrenia. Psychiatry research, 2015